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Bioinformatics interfaces computer science and molecular biology with the goal of storing, organizing and analyzing biological information. The Bioinformatics Unit at the W. M. Keck Center provides centralized databases for data management and various application tools for retrieving and analyzing the data


Services
EST and Genome Sequencing Analysis includes sequence processing, clustering, contig assembly, annotation, redundancy check, data and project management. The following web based tools are available:
  • Genome Project Management System (GPMS) is a web based database system for users in a high throughput sequencing project monitor progress and retrieve data.
  • High Throughput Sequences Pickup is a web site for non-GPMS users to retrieve sequence data.
  • GridBLAST is a web portal for running high throughput BLAST.
  • COMPASS is a web portal for predicting genome map locations of unmapped sequences in mammalian genome.
  • Batch Primer3 is a web portal for designing primers using Primer3 program.
  • Manatee is a microbial genome annotation system from TIGR. Under Development

Microarray Analysis includes data preprocessing, statistical test, database, annotation and data mining on different platforms (cDNA, Oligo, and Affymetrix) using programs such as R (Bioconductor), SAS, GeneSpring, etc.

General Consulting includes other analysis such as phylogenetic analysis, specific sequence pattern searching, sequence annotation, etc.

images/dot.gif (930 bytes) The functions of the Bioinformatics Unit:
  • Support for High Throughput DNA Sequencing and Functional Genomics Units
    The Bioinformatics Unit provides seamless data flow from data collection instruments to databases, reliable data storage and management, and easy data access by users. 
  • Development
    The Bioinformatics Unit is developing innovative data analysis tools, and visualization software and database resources for genomics research in collaboration with the Department of Computer Science and National Center for Supercomputing Application (NCSA).
  • Collaborative Research
    The Bioinformatics Unit is conducting interdisciplinary research with University of Illinois faculty from various departments in five different colleges. 
  • Training
    The Bioinformatics Unit will also provide training sessions and workshops for students and faculty to learn the basics of bioinformatics including using various tools for database queries, data analysis and data mining.

Projects

Bioinformatics Unit
Kiran Donthu, Ph.D.
330 Edward R. Madigan Laboratory, 1201 W. Gregory Drive, Urbana, IL 61801
Phone: (217) 244-7355     FAX: (217) 265-5066     Email: donthu@illinois.edu

Last edited: 20 DEC 2011